Table 2.

Adjusted baseline estimates and relative mean percent change at two, six, and twelve months follow-up in hip structural analysis narrow neck geometric parameters.

Time Point	Men			Women
Aerial BMD	% Change	95% CI	* P	% Change	95% CI	* P	** P	*** P
Baseline	0.62	(0.59, 0.66)	REF	0.67	(0.64, 0.70)	REF	0.109	0.418
Δ T2	−0.87	(−5.54, 3.78)	0.71	0.82	(−2.84, 4.51)	0.655	0.559
Δ T6	−0.90	(−6.40, 4.55)	0.742	0.60	(−2.85, 4.10)	0.728	0.643
Δ T12	−6.36	(−12.81, 0.06)	0.052	−0.14	(−4.05, 3.74)	0.939	0.11
CSA
Baseline	2.11	(1.98, 2.25)	REF	2.13	(1.98, 2.25)	REF	0.882	0.265
Δ T2	−1.52	(−6.17, 3.11)	0.518	−0.52	(−4.01, 2.96)	0.768	0.739
Δ T6	−2.47	(−7.75, 2.80)	0.357	−0.14	(−3.95, 3.66)	0.941	0.491
Δ T12	−6.33	(−12.47, −0.20)	0.043	1.37	(−3.31, 6.43)	0.565	0.049
OD
Baseline	3.53	(3.45, 3.61)	REF	3.30	(3.21, 3.39)	REF	0.004	0.807
Δ T2	−0.88	(−2.44, 0.66)	0.261	−1.42	(−2.92, 0.07)	0.063	0.683
Δ T6	−1.46	(−3.25, 0.32)	0.109	−1.03	(−2.76, 0.69)	0.239	0.694
Δ T12	0.52	(−1.32, 2.38)	0.575	1.35	(−1.38, 4.08)	0.332	0.649
SM
Baseline	1.22	(1.13, 1.31)	REF	1.09	(1.02, 1.17)	REF	0.087	0.245
Δ T2	−2.48	(−7.63, 2.64)	0.341	−1.27	(−5.14, 2.58)	0.515	0.678
Δ T6	−3.76	(−9.64, 2.10)	0.207	−0.53	(−5.03, 3.95)	0.813	0.371
Δ T12	−4.98	(−11.08, 1.10)	0.108	3.94	(−2.51, 10.42)	0.23	0.042
BR
Baseline	17.34	(16.31, 18.37)	REF	15.27	(14.40, 16.15)	REF	0.012	0.176
Δ T2	−1.20	(−6.22, 3.81)	0.636	−0.32	(−6.04, 5.38)	0.909	0.795
Δ T6	−0.47	(−6.87, 5.92)	0.884	−2.74	(−6.96, 1.46)	0.2	0.609
Δ T12	7.50	(0.65, 14.36)	0.032	−1.20	(−6.41, 4.00)	0.65	0.044

BMD: Bone Mineral Density; CSA: Cross Sectional Area; SM: Section Modulus; BR: Buckling Ratio.

^*P value for sex- and time-specific changes;

^**P values for the time-specific differences in change;

^***P value for the global test of the sex by time interaction.