Table 1.
Patient characteristics
| Total number of patients | Male | Female | p value | Non-obese | Obese | p value | |
|---|---|---|---|---|---|---|---|
| Total number of patients | 186 | 138 (74 %) | 48 | N/A | 148 | 38 | N/A |
| Male | 138 | N/A | N/A | N/A | 111 | 27 | N/A |
| Female | 48 | N/A | N/A | N/A | 37 | 11 | N/A |
| Age (years), mean (SD) | 64.2 (11.6) | 64.2 (10.8) | 64.1 (13.5) | 0.962 | 64.4 (12.1) | 63.1 (9.3) | 0.535 |
| Height (cm), mean (SD) | 175.2 (9.9) | 179.0 (7.4) | 164.3 (7.9) | <0.01 | 175.6 (10.0) | 173.5 (9.6) | 0.225 |
| Weight (kg), mean (SD) | 82.4 (14.1) | 86.1 (11.9) | 71.9 (14.8) | <0.01 | 78.6 (12.3) | 97.4 (10.3) | <0.01 |
| BMI (kg/m2), mean (SD) | 26.8 (3.8) | 26.8 (3.2) | 26.6 (5.2) | 0.793 | 25.4 (2.5) | 32.4 (2.6) | <0.01 |
| WC (cm), mean (SD) | 101.9 (10.8) | 102.6 (9.7) | 99.7 (13.3) | 0.168 | 98.8 (9.4) | 113.8 (6.7) | <0.01 |
| HC (cm), mean (SD) | 106.1 (8.7) | 105.3 (7.4) | 108.2 (11.5) | 0.108 | 103.5 (6.9) | 116.2 (7.6) | <0.01 |
| WHR, mean (SD) | 0.96 (0.07) | 0.97 (0.06) | 0.92 (0.07) | <0.01 | 0.95 (0.07) | 0.98 (0.06) | 0.025 |
| IAP (mmHg), mean (SD) | 9.1 (4.4) | 9.2 (4.0) | 8.6 (5.2) | 0.398 | 8.7 (4.2) | 10.4 (4.7) | 0.031 |
| IAP ≥ 12 | 50 | 40 | 10 | 0.086 | 35 | 15 | 0.667 |
| Pre-operative creatinine (umol/l), mean (SD) | 86.0 (19.7) | 89.3 (19.5) | 76.4 (17.3) | <0.01 | 85.5 (19.4) | 87.7 (21.1) | 0.546 |
| Pre-operative CRP (mg/l), mean (SD) | 7.3 (13.2) | 7.2 (13.3) | 7.6 (13.3) | 0.884 | 6.7 (12.8) | 9.7 (14.7) | 0.211 |
| Pre-operative eGFR (ml/min/1.73 m2) | 78.2 (17.2) | 79.6 (16.8) | 73.9 (17.8) | 0.046 | 78.5 (17.0) | 77.0 (17.9) | 0.627 |
| Postoperative creatinine (umol/l), mean (SD) | 74.1 (21.8) | 77.5 (21.5) | 64.4 (19.9) | <0.01 | 73.2 (22.0) | 77.9 (21.0) | 0.230 |
| Postoperative CRP (mg/l), mean (SD) | 49.5 (30.1) | 52.2 (31.6) | 41.9 (23.8) | 0.040 | 46.5 (26.6) | 61.1 (39.0) | 0.034 |
| Postoperative eGFR (ml/min/1.73 m2) | 88.6 (18.6) | 89.2 (18.3) | 86.7 (19.8) | 0.426 | 89.4 (18.8) | 85.6 (17.8) | 0.265 |
| Delta eGFR, mean (SD) (ml/min/1.73 m2) | 10.4 (10.2) | 9.6 (9.7) | 12.8 (11.4) | 0.059 | 10.9 (9.9) | 8.6 (11.4) | 0.223 |
| Comorbidity Chronic diagnosis at admission ICU | |||||||
| COPD | 17 | 13 | 4 | N/A | 14 | 3 | N/A |
| Chronic cardiovascular insufficiency | 10 | 8 | 2 | N/A | 8 | 2 | N/A |
| Immunological insufficiency | 8 | 6 | 2 | N/A | 4 | 4 | N/A |
| Metastasized neoplasm | 3 | 2 | 1 | N/A | 2 | 1 | N/A |
| Respiratory insufficiency | 1 | 1 | 0 | N/A | 1 | 0 | N/A |
| Hemotological malignancy | 1 | 1 | 0 | N/A | 1 | 0 | N/A |
| Diagnosis at admission ICU | |||||||
| Cardiovascular resuscitation | 1 | 1 | 0 | N/A | 1 | 0 | N/A |
| Dysrhythmia | 2 | 1 | 1 | N/A | 2 | 0 | N/A |
| Mechanical ventilation at admission | 186 | 138 | 48 | N/A | 148 | 38 | N/A |
| Diabetes | 21 | 12 | 9 | 0.103 | 11 | 10 | 0.003 |
| Myocardial infarction | 40 | 34 | 6 | 0.119 | 32 | 8 | 1.0 |
| Diagnosis 24 h after ICU admission | |||||||
| Acute kidney injury | 1 | 1 | 0 | N/A | 1 | 0 | N/A |
| Confirmed infection | 1 | 1 | 0 | N/A | 1 | 0 | N/A |
| Vasoactive medication in first 24 h | 164 | 119 | 45 | 0.259 | 132 | 32 | 0.571 |
| Apache IV score, mean (SD) N = 184 | 42.8 (13.8) | 41.8 (15.0) | 43.7 (12.5) | 0.435 | 42.0 (15.3) | 43.4 (10.1) | 0.521 |
| Euro score, mean (SD) | 7.1 (7.6) | 6.4 (7.4) | 8.9 (7.9) | 0.050 | 7.6 (8.1) | 5.2 (4.7) | 0.024 |
| Surgery | |||||||
| CABG | 97 | 80 | 17 | N/A | 74 | 23 | N/A |
| CABG + valve | 16 | 9 | 7 | N/A | 13 | 3 | N/A |
| Valve | 58 | 40 | 18 | N/A | 49 | 9 | N/A |
| Aneurysm—thoracic aortic repair | 9 | 5 | 4 | N/A | 8 | 1 | N/A |
| Othera | 6 | 4 | 2 | N/A | 4 | 2 | N/A |
| Operating time (min), mean (SD) | |||||||
| N = 179 | 245.9 (88.1) | 247.7 (92.1) | 240.7 (76.0) | 0.642 | 240.9 (80.1) | 265.1 (113.1) | 0.138 |
| Perfusion time (min), mean (SD) | |||||||
| N = 117 | 149.8 (71.7) | 151.4 (78.0) | 146.0 (55.9) | 0.707 | 143.7 (64.5) | 177.6 (95.4) | 0.049 |
| Aorta occlusion time (min), mean (SD) | |||||||
| N = 101 | 104.9 (49.0) | 106.4 (53.3) | 101.7 (38.7) | 0.656 | 102.2 (45.7) | 116.5 (61.4) | 0.255 |
| ICU | |||||||
| Mechanical ventilation duration in hours, median (range) | 8.0 (187) | 7.0 (187) | 8.0 (91) | 0.402 | 8.0 (187) | 8.0 (85) | 0.335 |
| Reintubation within 72 h after detubation | 0 | 0 | 0 | N/A | 0 | 0 | N/A |
| Length of stay ICU in days, median (range) | 0.91 (19.4) | 0.91 (19.4) | 0.92 (6.1) | 0.588 | 0.91 (19.4) | 0.94 (5.2) | 0.060 |
p < 0.05 is significant
N/A not applicable
aIncludes pericardiectomy, congenital defect repair and ablation