Table 3. Absolute organ weights of animals exposed with DMAE in the acute toxicity study.
Parameter | Male (mg/kg) | Female (mg/kg) | ||||
---|---|---|---|---|---|---|
0 | 2,500 | 5,000 | 0 | 2,500 | 5,000 | |
Organ weights (g) | ||||||
Body weight (g) | 289.8±14.9 | 296.0±5.3 | 294.0±15.5 | 199.2±6.1 | 199.2±4.8 | 200.8±6.8 |
Liver | 9.94±1.14 | 10.90±0.86 | 10.73±0.58 | 6.93±0.38 | 6.77±0.83 | 6.99±0.20 |
Heart | 1.11±0.07 | 1.10±0.07 | 1.13±0.08 | 0.81±0.05 | 0.79±0.08 | 0.86±0.06 |
Spleen | 0.74±0.06 | 0.73±0.07 | 0.75±0.04 | 0.59±0.11 | 0.64±0.03 | 0.61±0.06 |
Lung | 1.75±0.24 | 1.74±0.17 | 1.71±0.17 | 1.30±0.09 | 1.36±0.17 | 1.41±0.24 |
Kidneys | 2.77±0.31 | 2.57±0.10 | 2.64±0.09 | 1.66±0.15 | 1.50±0.20 | 1.70±0.12 |
Adrenal glands | 0.05±0.01 | 0.04±0.02 | 0.03±0.01 | 0.04±0.02 | 0.06±0.01 | 0.06±0.01 |
Testes | 3.47±0.15 | 3.64±0.15 | 3.53±0.10 | |||
Epididymides | 0.80±0.15 | 0.76±0.05 | 0.84±0.05 | |||
Ovaries | 0.11±0.02 | 0.10±0.04 | 0.10±0.03 | |||
Uteri | 0.52±0.23 | 0.42±0.09 | 0.47±0.09 |
Values are expressed as mean±SD of five rats.