Table 4. Relative organ weights of animals exposed with DMAE in the acute toxicity study.
| Parameter | Male (mg/kg) | Female (mg/kg) | ||||
|---|---|---|---|---|---|---|
| 0 | 2,500 | 5,000 | 0 | 2,500 | 5,000 | |
| Organ weights (% of body weight) | ||||||
| Body weight (g) | 289.8±14.9 | 296.0±5.3 | 294.0±15.5 | 199.2±6.1 | 199.2±4.8 | 200.8±6.8 |
| Liver | 3.42±0.26 | 3.68±0.24 | 3.65±0.19 | 3.48±0.19 | 3.40±0.39 | 3.48±0.17 |
| Heart | 0.38±0.03 | 0.37±0.02 | 0.39±0.02 | 0.40±0.02 | 0.40±0.03 | 0.43±0.04 |
| Spleen | 0.25±0.02 | 0.25±0.02 | 0.26±0.03 | 0.30±0.06 | 0.32±0.02 | 0.31±0.03 |
| Lung | 0.60±0.07 | 0.59±0.06 | 0.58±0.06 | 0.66±0.04 | 0.69±0.10 | 0.70±0.10 |
| Kidneys | 0.95±0.08 | 0.87±0.03 | 0.90±0.05 | 0.83±0.08 | 0.75±0.08 | 0.85±0.04 |
| Adrenal glands | 0.02±0.01 | 0.02±0.01 | 0.01±0.00 | 0.02±0.01 | 0.03±0.00 | 0.03±0.01 |
| Testes | 1.20±0.05 | 1.23±0.07 | 1.20±0.05 | |||
| Epididymides | 0.27±0.05 | 0.26±0.02 | 0.28±0.02 | |||
| Ovaries | 0.05±0.01 | 0.05±0.02 | 0.05±0.01 | |||
| Uteri | 0.26±0.11 | 0.21±0.04 | 0.23±0.05 | |||
Values are expressed as mean±SD of five rats.