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. 2016 Oct 11;6:33927. doi: 10.1038/srep33927

Table 2. N-glycosylation site occupancies in health and liver disease conditions.

ID Sample OMIM entry Clinical score TRFE
HPT
IGHA1
IGHG2
mean SEM mean SEM mean SEM mean SEM
001 PMM2-CDG 601785 * 86 2.8 3 1.0 82 2.8 100 0.0
002 PMM2-CDG 601785 mild 90 2.1 32 4.6 83 1.0 100 0.0
003 PMM2-CDG 601785 mild/moderate 91 0.7 24 3.1 86 1.0 100 0.0
004 PMM2-CDG 601785 moderate 91 1.0 13 2.2 87 0.2 100 0.0
005 PMM2-CDG 601785 severe 84 1.8 3 0.5 86 2.1 100 0.0
034 AlG11-CDG 613661 * 94 0.1 28 1.2 90 2.7 100 0.0
036 AlLG1-CDG 608540 moderate 82 2.1 7 0.4 91 0.1 100 0.0
037 ALG6-CDG 603147 severe 85 0.5 3 0.3 90 0.5 100 0.0
038 MPDU1-CDG 604041 moderate/severe 91 0.5 12 3.4 87 1.7 100 0.0
039 RFT1-CDG 612015 severe 72 1.7 3 0.7 91 1.8 100 0.0
007 healthy na na 93 0.9 61 2.5 84 1.8 100 0.0
008 healthy na na 94 0.5 57 3.2 86 1.6 100 0.0
009 healthy na na 93 1.1 54 1.8 85 1.3 100 0.0
010 healthy na na 95 0.5 52 3.1 84 1.3 100 0.0
011 healthy na na 95 0.5 56 6.5 86 4.3 100 0.0
012 Steatosis nd <3 95 1.4 73 4.0 86 1.9 100 0.0
013 Steatosis nd <3 94 0.5 71 5.6 85 1.0 100 0.0
015 Steatosis nd <3 95 0.7 61 5.8 84 4.0 100 0.0
016 Steatosis nd <3 95 0.5 68 1.9 87 1.4 100 0.0
014 NASH nd 5 95 0.2 69 1.9 86 1.5 100 0.0
017 NASH nd 3 95 0.8 59 5.2 86 0.9 100 0.0
018 NASH nd 4 96 1.0 64 1.4 86 1.9 100 0.0
019 NASH nd 5–6 95 0.7 69 4.1 82 1.4 100 0.0
020 NASH nd 4 95 1.5 60 12.3 88 2.6 100 0.0
021 NASH nd 4 94 0.7 53 4.4 88 3.3 100 0.0
022 NASH nd 6 95 1.3 43 3.9 91 1.5 100 0.0
023 NASH nd * 94 0.7 58 11.5 90 2.0 100 0.0

The values for each glycosylation site are averaged from three technical replicates, starting with the serum sample preparation. SEM = standard error of mean. Average values derived from 5 samples from healthy serum, 4 liver steatosis samples and 8 NASH samples. OMIM = Online Mendelian Inheritance in Man, na = not applicable, nd = not determined, ID = unique sample identifier, TRFE = transferrin, HPT = haptoglobin, IGHA1 = human IgA1, IGHG2 = human IgG2, (*) = no clinical information available. The clinical score values are displayed according to Grünewald et al. or Kleiner et al. (NAFLD activity scores), respectively30,31.