Table 2. Basic parameters in subgroups.
Group 1 (n = 16) Before IVI | Group 2 (n = 15) Post-IVI ≤ 5 weeks | Group 3 (n = 15) Post-IVI > 5 weeks | P-value | |||
---|---|---|---|---|---|---|
1 vs 2 | 1 vs 3 | 2 vs 3 | ||||
Age (mean ± SD) | 79.63 ± 7.88 | 75.33 ± 8.38 | 76.47 ± 10.35 | 0.15 | 0.34 | 0.74a |
Female/male | 4/12 | 6/9 | 4/11 | 0.46 | 1.00 | 0.70b |
Latest IVI avastin/lucentis | not applicable | 9/6 | 11/4 | — | — | 0.70a |
AMD/myopic NV/PCV | 15/0/1 | 12/2/1 | 14/0/1 | 0.33 | 1.00 | 0.60a |
Follow-up months (mean ± SD) | 14.38 ± 6.89 | 12.14 ± 6.67 | 18.00 ± 11.30 | 0.37 | 0.29 | 0.09a |
No. of samples below detection limit of VEGF after IVI | 0 | 9 (60%) | 2 (13.3%) | — | — | < 0.05*b |
aKruskal-Wallis test.
bFisher’s two-tailed test.
IVI = intravitreal injection, AMD = age-related macular degeneration, NV = neovascularization, PCV = polypoidal choroidal vasculopathy, VEGF = vascular endothelial growth factor, SD = standard deviation.