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. 2016 Oct 11;6:34710. doi: 10.1038/srep34710

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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(a) Qualitative analysis of LIP-IND-ORA tissue distribution in the maternal uterus and liver, placenta and in the fetus of pregnant mice. Red: LIP-IND-ORA (lissamin rhodamin labeled phospholipid); Blue- DAPI, nuclear stain. (b) Quantification of the LIP-IND-ORA fluorescent signal in the tissues normalized to tissue auto-fluorescence using NIS elements. Quantitative biodistribution of liposome was obtained from at least 9 randomly selected fields per mouse of each organ. Mean ± SEM, n = 6. *p-value < 0.05, ^**p-value < 0.01 to fetus.