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. 2016 Oct 11;6:34710. doi: 10.1038/srep34710

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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To assess the shift in biodistribution in different formulations, IND was administered either in free form or within LIP-IND-ORA. IND concentrations in the maternal uterus and fetus were determined by LC-MS/MS analysis. Mean ± SEM, n = 6. ^**p-value < 0.01 to the levels of IND when the drug was administered via LIP-IND-ORA.