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. 2016 Oct 11;6:35117. doi: 10.1038/srep35117

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Typical example of Raman chemigram map (1156 cm⁻¹ band reference) of a mixed zone of thyroid tissue (blue-healthy; red-yellow-green–PTC): ((a)–dark field optical image, (b)–Raman map, (c)–average reference Raman spectrum corresponding to healthy tissue, (d)–average reference Raman spectrum corresponding to PTC tissue). The red square on the right side (a) corresponds to the investigated tissue area shown on the left (b). The scale bars are expressed in μm.