Table 2. Incidence of nephrotoxicity and vancomycin trough concentration outcomes.

Outcomes	Pre-vancomycin nomogram (n = 100)	Post-vancomycin nomogram (n = 100)	P*
Nephrotoxicity, %	16	14	.197
Vancomycin trough, mg/L, mean (±SD)	19.1 (±9.3)	17.6 (±8.1)	NS
Percent of patients with initial trough within target range, 15–20 mg/L	29.1	21.7	<.001
Percent of patients eventually achieving target trough, 15–20 mg/L	39.5	37	NS
Percent of patients with troughs >20 mg/L	45.3	43.5	NS
Percent of patients with troughs <15 mg/L	46.5	62	<.001
Mean time to achieve target trough, days	5.74	5.58	NS

Note: NS = not statistically significant.

^*Statistical test used: chi-square for categorical variables; Student t test for continuous variables. Level of significance considered as P < .05.