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. 2016 Oct 10;9:212. doi: 10.1186/s13068-016-0630-y

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Dynamics labeling of central metabolites. Labeling dynamics in selected metabolites postpulse of ¹³C₆-glucose into a Wild Type and b WH04. c Relative metabolite peak ratio of central metabolites in WT and ED mutant strains. The glycolysis key node (3PG) is used as the base of comparison. d Ratio of WT pool size to mutant pool size for G6P, 6PG, and MAL. The metabolite pools in two mutants, ∆pfkA (JW3887) and WH04, were measured via isotopomer ratio analysis. Asterisk 6PG measurement for WT was below detection