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. 2016 Oct 10;17:790. doi: 10.1186/s12864-016-3143-y

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Iterative signature algorithm (ISA) parameter selection. a Number of modules generated for different combinations of gene and sample thresholds and for the merged results. b Percentage of modules enriched with gene ontology (GO) terms for different threshold values and merged results. “All,” merged result from all threshold combinations; %M_GO, the percentage of modules enriched with GO terms; N_m, the number of modules generated