Table 1.
Baseline characteristics of patients in the full analysis set
| Placebo | SB (AUN/ml) | ||||
|---|---|---|---|---|---|
| 3333 | 10 000 | 20 000 | 40 000 | ||
| n | 52 | 54 | 56 | 53 | 54 |
| Age [years, mean (SD)] | 36.4 (10.0) | 36.5 (10.2) | 34.9 (10.0) | 35.8 (10.0) | 36.2 (10.8) |
| Range | 20–58 | 19–59 | 18–58 | 19–58 | 19–57 |
| Weight [kg, mean (SD)] | 74.5 (14.3) | 77.1 (16.3) | 72.4 (14.5) | 76.1 (17.7) | 76.0 (16.9) |
| Range | 47–104 | 50–112 | 49–113 | 50–118 | 50–120 |
| Height [cm, mean (SD)] | 173.6 (10.6) | 173.1 (10.2) | 172.1 (9.8) | 172.5 (8.3) | 173.7 (9.5) |
| Range | 152–200 | 150–195 | 154–192 | 154–189 | 158–195 |
| Gender M/F | 28/24 | 27/27 | 27/29 | 25/28 | 28/26 |
| SPT birch [mm, mean wheal size (SD)] | 8.2 (2.9) | 8.3 (2.8) | 8.4 (3.3) | 8.8 (4.0) | 8.8 (3.1) |
| Birch‐specific IgE [kU/l, mean (SD)] | 30.9 ± 27.2 | 40.8 ± 40.5 | 32.5 ± 32.0 | 33.5 ± 34.5 | 34.6 ± 35.1 |
| TNPT mean symptom score (SD) | 6.08 (1.78) | 5.75 (1.46) | 6.01 (1.47) | 5.79 (1.80) | 6.22 (1.70) |
| PNIF [l, mean (SD)] | 83.7 (35.5) | 85.8 (31.9) | 93.7 (43.3) | 91.3 (36.5) | 98.3 (43.9) |
n, number of patients in the full analysis set; SD, standard deviation; SPT, skin prick test; IgE, immunoglobulin E; TNPT, titrated nasal provocation test; PNIF, peak nasal inspiratory flow.