Table 1.
ITGs in hotspots and relationship with tumors
| Integrated times | ITGs in the hotspot and relationship with tumors | ||||
|---|---|---|---|---|---|
| Hotspot | HPV16/18 | HPV16 | HPV18 | Y | N |
| 1p36 | 11 | 11 | 0 | CASZ1, C1orf201, WASF2, ALPQTL2 | C1orf196 |
| 1q21 | 6 | 6 | 0 | RPS27, USP21, GOLPH3L | LOC645166 |
| 2q22 | 8 | 5 | 3 | LRP1B, PABPC1P2 | LOC151128 |
| 2q33 | 6 | 6 | 0 | ORC2, PARD3B, RTN4IP1 | |
| 3q26 | 9 | 9 | 0 | MECOM, MDS1, ATP11B, SOX2 | TNIK |
| 3q28 | 11 | 9 | 2 | TP63, LEPREL1, FAM79B, CLDN16, CLDN1 | |
| 6q21 | 6 | 6 | 0 | FIG4 | |
| 8p11 | 7 | 4 | 3 | ZNF703 | |
| 8q24 | 34 | 17 | 17 | POU5F1B, MYC, AGO2, GPAA1, RASSF6, DEPTOR | LOC727677 |
| 9q22 | 8 | 5 | 3 | FANCC | C9orf3 |
| 9q34 | 8 | 5 | 3 | Notch1, EGFL7 | SLC25A25 |
| 13q21 | 8 | 8 | 0 | DACH1 | |
| 13q22 | 12 | 10 | 2 | KLF5, KLF12 | |
| 14q24 | 9 | 6 | 3 | RNGTT, RAD51B, GLI2 | |
| 14q32 | 6 | 6 | 0 | BCL11B, TNFAIP2, SLC24A4 | |
| 17q12 | 7 | 7 | 0 | MED24, PLXDC1, IKZF3, GRB7, HNF1B | C‐CR7 |
| 17q21 | 7 | 5 | 2 | ERBB2, BRCA1, STARD3, EIF1, RARA | KRT40 |
| 17q23 | 14 | 8 | 6 | TMEM49, CGI‐147 | TUBD1 |
| 19p13 | 8 | 7 | 1 | PRKACA, NANOS3, ARID3A, HMHA1 | MOB3A, ZNF506, GATAD2A |
| 19q13 | 6 | 4 | 2 | CEACAM5 | LOC126235, Q8N6Q3 |
| 20p12 | 7 | 6 | 1 | MACROD2, FLRT3 | |
| Xp22 | 6 | 6 | 0 | STS, NHS, PDK3 | FAM48B2, VCX2 |
The bold genes have been reported to be tumor‐related based on NCBI database, whereas the underlined genes were recurrently integration‐targeted genes.
Abbreviations: Y: Yes; means that these genes had been reported to be a tumor‐related gene; N: no; means that there was no report about the relationship between this gene and tumors.