Table 6.
Diagnostic Performance of Echo RV Linear Dimensions for Right Ventricular Chamber Dilation on CMR*
| A. ASE Guideline Recommended Linear Cutoffs | ||||||
|---|---|---|---|---|---|---|
| Cutoff (mm) |
Sensitivity | Specificity | Accuracy | PPV | NPV | |
| Proximal RVOT width | 35 | 81% | 75% | 75% | 25% | 97% |
| Basal RV width | 41 | 81% | 84% | 84% | 36% | 98% |
| Mid RV width | 35 | 46% | 92% | 88% | 39% | 94% |
| RV length | 83 | 77% | 67% | 68% | 20% | 96% |
| Distal RVOT width | 27 | 68% | 80% | 79% | 27% | 96% |
| B. Cohort-derived Linear Cutoffs** | |||||||
|---|---|---|---|---|---|---|---|
| AUC (95% CI) | Cutoff (mm/m2) |
Sensitivity | Specificity | Accuracy | PPV | NPV | |
| Proximal RVOT width | 0.86 (0.79–0.93); p<0.001 | 18.7 | 77% | 82% | 82% | 31% | 97% |
| Basal RV width | 0.87 (0.78–0.95); p<0.001 | 22.4 | 77% | 89% | 87% | 42% | 97% |
| Mid RV width | 0.82 (0.73–0.92); p<0.001 | 16.7 | 77% | 84% | 83% | 33% | 97% |
| RV length | 0.78 (0.69–0.87); p<0.001 | 45.8 | 54% | 82% | 79% | 24% | 94% |
| Distal RVOT width | 0.77 (0.66–0.88); p<0.001 | 14.2 | 72% | 82% | 81% | 29% | 97% |
*
RV dilation assessed at end-diastole on both echo and CMR
**
optimized for sensitivity using a minimum specificity cutoff of 80%