Table 3.
Sensitivity | Specificity | Accuracy | Positive Predictive Value | Negative Predictive Value | |
---|---|---|---|---|---|
Non-Contrast Echo | 33% (8/24) | 94% (91/97) | 82% (99/121) | 57% (8/14) | 85% (91/107) |
Contrast Echo§ | 61% (14/23)† | 99% (96/97) | 92% (110/120)‡ | 93% (14/15) | 91% (96/105) |
Cine-CMR | 79% (19/24)§ | 99% (96/97) | 95% (115/121)§ | 95% (19/20) | 95% (96/101) |
Indices calculated using DE-CMR as the standard for LV thrombus
p < 0.05 (vs. non-contrast echo),
p < 0.01 (vs. non-contrast echo),
p ≤ 0.001 (vs. non-contrast echo)
One patient (with thrombus by non-contrast echo, cine-CMR, and DE-CMR) could not undergo the contrast echo component of the protocol due to contraindications to the echo contrast agent in the interim between study consent and imaging (decompensated heart failure)8.