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. 2016 Oct 10;16:781. doi: 10.1186/s12885-016-2820-1

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — Specific ALDH1A3 KO impairs NB cell clonogenic properties. a-c Impact of ALDH1A3 specific KO was analyzed on the proliferation (a), clonogenic (b), and TIC self-renewal (c) capacities. a Mean OD at 405 nm ± SD of 3 experiments performed in quadruplicates. b Mean of relative colony numbers ± SD of 3 experiments performed in duplicates (unpaired t-test *p < 0.05). c Mean ratio of cell number/cell plated ± SD of 3 experiments performed in duplicates in pooled s1 to s3 passages (s1-s3) (unpaired t-test **p ≤ 0.005)