Table 1.
Distribution of ataxia phenotypes by the KCNJ10:c.627C > G genotypes for Parson Russell (PRT) und Jack Russell Terriers (JRT)
| Breed | Phenotype | KCNJ10:c.627C > G | |||
|---|---|---|---|---|---|
| n | C/C | C/G | G/G | ||
| PRT | A | 12 | 1 | 0 | 11 |
| B | 4 | 1 | 0 | 3 | |
| C | 2 | 1 | 0 | 1 | |
| D | 20 | 7 | 13 | 0 | |
| E | 3 | 1 | 2 | 0 | |
| F | 36 | 27 | 7 | 2 | |
| Subtotal | 77 | 38 | 22 | 17 | |
| JRT | A | 0 | 0 | 0 | 0 |
| B | 3 | 1 | 1 | 1 | |
| C | 0 | 0 | 0 | 0 | |
| D | 0 | 0 | 0 | 0 | |
| E | 0 | 0 | 0 | 0 | |
| F | 6 | 0 | 6 | 0 | |
| Subtotal | 9 | 1 | 7 | 1 | |
A: hereditary ataxia clinically and histopathologically diagnosed, B: clinical signs of ataxia, C: clinical signs of ataxia, according to the medical records of the veterinary clinic and the report of the owner, D: unaffected dogs, E: unaffected dogs, but affected dogs in progeny or siblings, F: no information on health status; the phenotype group A contains 4 PRT shown in the pedigree (Pedigree numbers (P.n.) 14, 15, 16, 17, see Additional file 12), group D contains 7 PRT (P.n. 2, 6, 7, 8, 9, 10, 11, see Additional file 12) and group F includes 6 PRT (P.n. 1, 3, 4, 5, 12, 13, see Additional file 12)