Table 2.
Cox-regression analysis of various prognostic parameters in patients for all patients
| Factor | Univariate | Multivariate | ||
|---|---|---|---|---|
| HR (95 % CI) | P value | HR (95 % CI) | P value | |
| Sex | ||||
| Male | Reference | |||
| Female | 0.883 (0.581–1.340) | 0.558 | – | – |
| Age | ||||
| ≥60 | Reference | |||
| <60 | 2.077 (1.375–3.139) | 0.001 | 1.561 (1.009–2.417) | 0.046 |
| Tumor size (cm) | ||||
| <5 | Reference | |||
| ≥5 | 2.277 (1.410–3.678) | 0.001 | 2.091 (1.249–3.502) | 0.005 |
| TPX2 expression | ||||
| Negative | Reference | |||
| Positive | 3.703 (2.303–5.956) | 0.001 | 4.708 (2.800–7.917) | 0 |
| AJCC tumor stage | ||||
| I | Reference | |||
| II | 1.971 (0.840–4.624) | 0.119 | – | – |
| III | 2.268 (1.081–4.756) | 0.030 | – | – |
| IV | 2.666 (0.963–7.382) | 0.059 | – | – |
| N stage | ||||
| 0 | Reference | 0 | ||
| 1 | 4.022 (1.955–8.274) | 0.000 | 3.122 (1.474–6.611) | 0.003 |
| 3 | 7.015 (3.421–14.386) | 0.000 | 5.858 (2.731–12.566) | 0 |
| Distant metastasis | ||||
| No | Reference | |||
| Yes | 0.855 (0.346–2.110) | 0.733 | – | – |
| Infiltration | ||||
| No | Reference | |||
| Yes | 2.023 (0.639–6.402) | 0.231 | – | – |