Table 2.
HRs for BC-specific mortality associated with BMI and WHR, in the CBCS Phases I and II
Variable | Deaths/N | Model 1 HR (95 % CI) |
Model 2 HR (95 % CI) |
Model 3 HR (95 % CI) |
---|---|---|---|---|
BMI | ||||
All BC patients | ||||
<25 kg/m2 | 84/395 | 1 | 1 | 1 |
25 to <30 kg/m2 | 79/308 | 1.27 (0.91, 1.78) | 1.21 (0.86, 1.71) | 1.07 (0.76, 1.52) |
≥30 kg/m2 | 106/411 | 1.06 (0.75, 1.48) | 1.01 (0.71, 1.44) | 0.97 (0.68, 1.37) |
Basal-like | ||||
<25 kg/m2 | 10/53 | 1 | 1 | 1 |
25 to <30 kg/m2 | 20/62 | 2.03 (0.85, 4.84) | 2.18 (0.85, 5.54) | 1.40 (0.56, 3.48) |
≥30 kg/m2 | 30/83 | 2.21 (0.94, 5.21) | 2.44 (0.97, 6.12) | 1.67 (0.69, 4.05) |
Luminal | ||||
<25 kg/m2 | 53/268 | 1 | 1 | 1 |
25 to <30 kg/m2 | 42/198 | 1.16 (0.74, 1.81) | 1.07 (0.68, 1.70) | 1.04 (0.66, 1.64) |
≥30 kg/m2 | 55/251 | 0.95 (0.60, 1.49) | 0.86 (0.53, 1.39) | 0.84 (0.52, 1.36) |
WHR | ||||
All BC patients | ||||
<0.77 | 61/284 | 1 | 1 | 1 |
0.77 to < 0.84 | 94/389 | 1.09 (0.77, 1.54) | 1.08 (0.76, 1.55) | 0.95 (0.66, 1.36) |
≥0.84 | 118/451 | 1.14 (0.79, 1.65) | 1.12 (0.76, 1.64) | 0.91 (0.62, 1.34) |
Basal-like | ||||
<0.77 | 8/36 | 1 | 1 | 1 |
0.77 to <0.84 | 29/81 | 1.49 (0.64, 3.46) | 1.05 (0.43, 2.56) | 1.35 (0.58, 3.15) |
≥0.84 | 24/83 | 0.98 (0.38, 2.49) | 0.64 (0.24, 1.74) | 0.94 (0.37, 2.41) |
Luminal | ||||
<0.77 | 41/201 | 1 | 1 | 1 |
0.77 to <0.84 | 44/240 | 0.92 (0.57, 1.47) | 0.94 (0.58, 1.53) | 0.75 (0.46, 1.22) |
≥0.84 | 67/282 | 1.15 (0.71, 1.85) | 1.21 (0.73, 2.08) | 0.82 (0.50, 1.36) |
Model 1 was adjusted for age, race, study phase, income, education, physical activity, alcohol intake, smoking, and parity; model 2 was additionally adjusted for WHR (in model of BMI) or BMI (in model of WHR); model 3 was additionally adjusted for tumor stage, tumor size, lymph node status, histological-type, and variables in model 1