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. Author manuscript; available in PMC: 2016 Oct 11.
Published in final edited form as: J Am Acad Dermatol. 2012 Oct 18;68(3):395–403. doi: 10.1016/j.jaad.2012.09.012

Fig 1.

Fig 1

The 180-kd bullous pemphigoid (BP) antigen-2 (BP180) recombinant proteins. Schematic representation of BP180, type II transmembrane (TM) protein containing globular intracellular domain (ICD) and extracellular domain (ECD) with 15 interrupted collagenous regions. Noncollagenous 16A (NC16A) region contains immunodominant autoantibody epitope in BP. Recombinant fusion proteins are indicated by amino acid (AA) residues of protein. AA 490 to 1497 (sec180) represents entire ECD of protein and AA 567 to 1497 (delNC16A) represents ECD of BP180 with NC16A region deleted.