Table 2.
Mean values of exercise and echocardiographic findings of the studied subjects
| SLE (n=56) | Control (n=50) | p | |
|---|---|---|---|
| Age: | |||
| Mean±SD | 35.4±11.9 | 34.9±10.1 | >0.05 |
| 95% CI | 31.3–42.5 | 31.2–43.6 | |
|
| |||
| Sex: male/female | 10/46 | 3/25 | >0.05 |
|
| |||
| Disease duration | 8.6±3.7 (6.9–10.3) | ||
|
| |||
| Exercise: | |||
| Duration (m.) Mean±SD | 12.38±2.1 | 12.6±3.5 | >0.05 |
| 95% CI | 11.4–13.4 | 11.2–14 | |
| METs Mean±SD | 8.5±1.6 | 8.6±1.7 | >0.05 |
| 95% CI | 7.7–9.2 | 7.9–9.3 | |
|
| |||
| Cardiac function: | |||
| LV Systolic: | |||
| EF% Mean±SD | 62.6±3.8 | 64.2±14.6 | >0.05 |
| 95% CI | 60.8–64.4 | 58.2–70.2 | |
|
| |||
| RV Systolic: | |||
| TAPSE Mean±SD: | 18.8±3.9 | 20.6±0.7 | <0.05 |
| 95% CI systolic | 16.2–21.4 | 20.3–20.9 | |
|
| |||
| PWD: | |||
| Mitral: | |||
| E Mean±SD | 77.9±19.5 | 80.4±14.1 | >0.05 |
| 95% CI | 68.7–86.9 | 74.6–86.2 | |
| A Mean±SD | 71.8±18.5 | 50.3±11.4 | <0.0001 |
| 95% CI | 63.7–80.5 | 45.6–55 | |
| E/A Mean±SD | 1.16±0.43 | 1.59±0.6 | <0.0001 |
| 95% CI | 0.96–1.36 | 1.34–1.84 | |
|
| |||
| Tricuspid: | |||
| E Mean±SD | 62.7±8 | 59.3±7.9 | 0.08 |
| 95% CI | 58.9–66.5 | 56.04–62.6 | |
| A Mean±SD | 35.9±10.9 | 31±8 | <0.05 |
| 95% CI | 30.8–40.9 | 27.7–34.3 | |
| E/A Mean±SD | 1.86±0.46 | 1.91±0.6 | >0.05 |
| 95% CI | 1.64–2.1 | 1.66–2.16 | |
|
| |||
| Mitral TDI: | |||
| Lateral annulus: | |||
| E′ Mean±SD | 12.9±3.6 | 19.4±3.1 | <0.0001 |
| 95% CI | 11.2–14.6 | 18.1–20.7 | |
| A′ Mean±SD | 8.8±3.7 | 10.01±2.3 | >0.05 |
| 95% CI | 7.1–10.6 | 9.1–10.9 | |
| E′/A′ Mean±SD | 1.68±0.69 | 1.94±0.4 | 0.08 |
| 95% CI | 1.36–2 | 1.77–2.1 | |
|
| |||
| Medial annulus: | |||
| E′ Mean±SD | 11.6±2.4 | 12.8±1.9 | <0.05 |
| 95% CI | 10.4–12.7 | 12.01–13.6 | |
| A′ Mean±SD | 8.7±2.9 | 10.39±1.8 | <0.001 |
| 95% CI | 7.3–10 | 9.6–11.1 | |
| E′/A′ Mean±SD | 1.45±0.48 | 1.23±0.3 | <0.05 |
| 95% CI | 1.2–1.67 | 1.1–1.35 | |
|
| |||
| Tricuspid TDI: | |||
| Medial annulus: | |||
| E′ Mean±SD | 12.4±3.4 | 14.7±2.9 | <0.001 |
| 95% CI | 10.1–14.7 | 13.5–15.9 | |
| A′ Mean±SD | 10.8±2.9 | 12.4±3.5 | <0.05 |
| 95% CI | 3.48–3.8 | 10.9–13.8 | |
| E′/A′ Mean±SD | 1.37±0.55 | 1.18±0.34 | >0.05 |
| 95% CI | 0.98–1.77 | 1.04–1.3 | |
|
| |||
| Lateral annulus: | |||
| E′ Mean±SD | 12.6±3.5 | 14.5±3.2 | <0.05 |
| 95% CI | 10.9–14.2 | 13.8–15.9 | |
| A′ Mean±SD | 9.7±3.5 | 12.5±3.6 | <0.001 |
| 95% CI | 8.1–11.4 | 11–13.3 | |
| E′/A′ Mean±SD | 1.5±0.83 | 1.15±0.3 | <0.01 |
| 95% CI | 1.12–1.88 | 1.25–1.2 | |
E: early diastolic filling velocity (cm/s); A: late diastolic filling velocity (cm/s); E/A ratio: early (E) to late (A) ventricular filling velocities; LV: left ventricle; RV: right ventricle; EF: ejection fraction; TAPSE: tricuspid annular plane systolic excursion (mm); PWD: pulsed wave Doppler; TDI: tissue Doppler image