Table 1.
Calcium, phosphorus, and renal function according to the time course from denosumab administration
| Time from denosumab administration | 0 | 4 week | 7 week | 4 months | 6 months | 7 months |
| Corrected calcium (mg/dL) | 10.2 | 10 | 10 | 9.8 | 10.3 | 6.7 |
| Phosphorus (mg/dL) | 4 | 3.5 | 3.2 | 3.5 | 3.7 | 2.1 |
| Creatinine (mg/dL) | 0.96 | 1.18 | 1.14 | 1.07 | 1.11 | 0.97 |
| Estimated GFR for the Japanese | 44 | 35 | 36 | 39 | 37 | 43 |
| Estimated GFR from the CG | 35 | NA | 29 | NA | NA | 29 |
| Body weight (kg) | 42.1 | NA | 41.5 | NA | NA | 35.0 |
GFR: glomerular filtration rate (mL·min−1·1.73 m−2); CG: cockcroft–gault equations; NA: not available