Table 1. Mean total number of cases averted after 15 y across 1,500 simulations, with noisy vaccination trajectories and mean total number of TCs and cases averted per TC for vaccination scenarios with the stated trigger, 20% coverage, and a 3-mo lag between trigger and vaccination.
Cases Averted (95% CI) | Average Number of TCs (95% CI) | Cases Averted per TC (95% CI) | |
---|---|---|---|
Yemen-like (73% routine coverage, 38 births per 1,000) | |||
10 cases | 27,705 (24,780–30,631) | 2.18 (2.10–2.25) | 12,736 (11,322–14,150) |
25 cases | 28,613 (25,722–31,505) | 2.09 (2.02–2.16) | 13,691 (12,223–15,158) |
10% s in 2–5 y olds | 83,722 (81,247–86,198) | 9.81 (9.77–9.85) | 8,537 (8,282–8,792) |
15% s in 2–5 y olds | 68,084 (65,336–70,832) | 7.18 (7.13–7.24) | 9,480 (9,090–9,869) |
15% s in 2 y olds | 89,173 (86,768–91,577) | 11.01 (10.97–11.06) | 8,098 (7,877–8,319) |
Niger-like (71% routine coverage, 48 births per 1,000) | |||
10 cases | 18,269 (16,363–20,175) | 2.12 (2.06–2.19) | 8,612 (7,675–9,549) |
25 cases | 18,422 (16,479–20,364) | 1.95 (1.88–2.01) | 9,470 (8,423–10,516) |
10% s in 2–5 y olds | 52,718 (51,022–54,414) | 10.15 (10.11–10.20) | 5,193 (5,024–5,362) |
15% s in 2–5 y olds | 41,124 (39,280–42,968) | 7.53 (7.47–7.58) | 5,463 (5,214–5,711) |
15% s in 2 y olds | 56,207 (54,570–57,844) | 11.45 (11.41–11.48) | 4,910 (4,766–5,054) |
Nepal-like (86% routine coverage, 24 births per 1,000) | |||
10 cases | 712 (571–852) | 1.39 (1.32–1.46) | 513 (408–617) |
25 cases | 582 (436–728) | 0.91 (0.85–0.96) | 640 (475–806) |
10% s in 2–5 y olds | 1,093 (960–1226) | 5.03 (4.98–5.09) | 217 (191–244) |
15% s in 2–5 y olds | 416 (258–574) | 1.20 (1.16–1.25) | 346 (214, 478) |
15% s in 2 y olds | 701 (554–848) | 2.18 (2.12–2.24) | 322 (254, 389) |
Zambia-like (91% routine coverage, 46 births per 1,000) | |||
10 cases | 599 (464–735) | 1.07 (1.01–1.13) | 561 (430–692) |
25 cases | 459 (320–598) | 0.74 (0.69–0.79) | 621 (429–813) |
10% s in 2–5 y olds | 744 (612–876) | 3.72 (3.67–3.77) | 200 (164–236) |
15% s in 2–5 y olds | 108 (−70 to 285) | 0.38 (0.35–0.41) | 284 (−185 to 752) |
15% s in 2 y olds | 326 (174–479) | 0.88 (0.83–0.92) | 373 (197–549) |
Abbreviations: s, seropositive