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. 2016 Oct 11;13(10):e1002144. doi: 10.1371/journal.pmed.1002144

Table 1. Mean total number of cases averted after 15 y across 1,500 simulations, with noisy vaccination trajectories and mean total number of TCs and cases averted per TC for vaccination scenarios with the stated trigger, 20% coverage, and a 3-mo lag between trigger and vaccination.

Cases Averted (95% CI) Average Number of TCs (95% CI) Cases Averted per TC (95% CI)
Yemen-like (73% routine coverage, 38 births per 1,000)
10 cases 27,705 (24,780–30,631) 2.18 (2.10–2.25) 12,736 (11,322–14,150)
25 cases 28,613 (25,722–31,505) 2.09 (2.02–2.16) 13,691 (12,223–15,158)
10% s in 2–5 y olds 83,722 (81,247–86,198) 9.81 (9.77–9.85) 8,537 (8,282–8,792)
15% s in 2–5 y olds 68,084 (65,336–70,832) 7.18 (7.13–7.24) 9,480 (9,090–9,869)
15% s in 2 y olds 89,173 (86,768–91,577) 11.01 (10.97–11.06) 8,098 (7,877–8,319)
Niger-like (71% routine coverage, 48 births per 1,000)
10 cases 18,269 (16,363–20,175) 2.12 (2.06–2.19) 8,612 (7,675–9,549)
25 cases 18,422 (16,479–20,364) 1.95 (1.88–2.01) 9,470 (8,423–10,516)
10% s in 2–5 y olds 52,718 (51,022–54,414) 10.15 (10.11–10.20) 5,193 (5,024–5,362)
15% s in 2–5 y olds 41,124 (39,280–42,968) 7.53 (7.47–7.58) 5,463 (5,214–5,711)
15% s in 2 y olds 56,207 (54,570–57,844) 11.45 (11.41–11.48) 4,910 (4,766–5,054)
Nepal-like (86% routine coverage, 24 births per 1,000)
10 cases 712 (571–852) 1.39 (1.32–1.46) 513 (408–617)
25 cases 582 (436–728) 0.91 (0.85–0.96) 640 (475–806)
10% s in 2–5 y olds 1,093 (960–1226) 5.03 (4.98–5.09) 217 (191–244)
15% s in 2–5 y olds 416 (258–574) 1.20 (1.16–1.25) 346 (214, 478)
15% s in 2 y olds 701 (554–848) 2.18 (2.12–2.24) 322 (254, 389)
Zambia-like (91% routine coverage, 46 births per 1,000)
10 cases 599 (464–735) 1.07 (1.01–1.13) 561 (430–692)
25 cases 459 (320–598) 0.74 (0.69–0.79) 621 (429–813)
10% s in 2–5 y olds 744 (612–876) 3.72 (3.67–3.77) 200 (164–236)
15% s in 2–5 y olds 108 (−70 to 285) 0.38 (0.35–0.41) 284 (−185 to 752)
15% s in 2 y olds 326 (174–479) 0.88 (0.83–0.92) 373 (197–549)

Abbreviations: s, seropositive