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. 2016 Oct 11;11(10):e0164528. doi: 10.1371/journal.pone.0164528

Fig 3. Effects of atorvastatin on the expression of NF-κB, IL-6, iNOS, TNFαR1 and TGFβ1 in the renal cortical tissue.

Fig 3

Immunoblot analysis for expressions of NF-κB in the whole cell lysate fraction (A); NF-κB in nuclear fraction (B); IL-6 in whole cell lysate fraction (C); iNOS in whole cell lysate fraction (D); TNFαR1 in membrane fraction (E) and TGFβ1 in whole cell lysate fraction (F) in renal cortical tissues normalized to ß-actin. Lamin b1 or Na+-K+ ATPase was used as a marker for the nuclear or membrane fraction, respectively. Bar graph indicates mean ± SEM. (n = 6 rats in each group). *P < 0.05 compared to the control group. #P < 0.05 compared to the gentamicin-treated group. †P < 0.05 compared to the pretreatment group. C: control group; G: gentamicin-treated group; Pre: atorvastatin pretreatment group; Delayed: delayed treatment group and Ator: atorvastatin group.