Table 4. Correlation of baseline aging biomarkers with chronological age and clinical aging (according to LOFS).
| Chronological age (years) | Clinical aging (LOFS) | |||||
|---|---|---|---|---|---|---|
| Spearman correlation | p-value | N | Spearman correlation | p-value | N | |
| Telomere length | −0.11 | 0.32 | 86 | −0.27 | 0.01 | 85 |
| IL-6 | 0.32 | <0.01 | 108 | −0.21 | 0.03 | 106 |
| IL-10 | −0.03 | 0.78 | 101 | −0.05 | 0.62 | 99 |
| IGF-1 | −0.01 | 0.33 | 106 | −0.03 | 0.75 | 104 |
| TNF-α | 0.34 | <0.01 | 108 | −0.18 | 0.06 | 106 |
| MCP-1/CCL-2 | 0.18 | 0.07 | 107 | −0.14 | 0.16 | 105 |
| RANTES/CCL-5 | −0.01 | 0.88 | 107 | 0.16 | 0.10 | 105 |
Abbreviations. LOFS : Leuven Oncogeriatric Frailty Score; IL-6 : Interleukin-6; IL-10 : Interleukin-10; IGF-1 : Insulin Like Growth Factor-1; TNF-α : Tumor Necrosis Factor-α; MCP-1/CCL2 : Monocyte chemotactic protein-1/Chemokine (C-C motif) ligand 2; RANTES/CCL5 : Regulated Upon Activation, Normal T cell Expressed and presumably Secreted/ Chemokine (C-C motif) Ligand 5