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. 2016 May 11;7(21):30155–30165. doi: 10.18632/oncotarget.9310

Figure 2. Depletion of Zfp207 impairs spindle formation and chromosome alignment in mouse oocytes.

Figure 2

A. Representative images of normal and abnormal spindle morphologies and chromosome alignment in mouse oocytes. Oocytes were immnunostained with α-tubulin-FITC antibody to visualize spindle and counterstained with PI to visualize chromosome. Scale bar, 20μm. B. The rate of aberrant spindles was recorded in the control, Zfp207-KD and rescue oocytes. C. The rate of misaligned chromosomes was recorded in the control, Zfp207-KD and rescue oocytes. Data were presented as mean percentage (mean ± SEM) of at least three independent experiments. Asterisk denotes statistical difference at a p < 0.05 level of significance.