Table 2. Hot spots mutations found by next-generation sequencing in KIT/PDGFRA wild-type GISTs.

Case	Exon of gene	Mutation type	MutRatio*
2014-BZ0157	11 of KIT	Del 557–558	12.1%
2014-BZ0027	11 of KIT	L576P	20.4%
2014-BZ0129	11 of KIT	L576P	17.7%
2014-BZ0132	11 of KIT	W557R	22.8%
2014-BZ0069	11 of KIT	Del 557–558	16.9%
2014-BZ0184	11 of KIT	L576P	11.8%
2014-BZ0020	11 of KIT	W557R	24.1%
2014-BZ0075	11 of KIT	Del 579	14.4%
2014-BZ0093	11 of KIT	W557G	18.4%
2014-BZ0019	11 of KIT	V559D	23.5%
2014-BZ0021	11 of KIT	L576P	10.5%
2014-BZ0128	11 of KIT	L576P	11.7%
2014-BZ0166	11 of KIT	L576P	13.4%
2014-BZ0017	11 of KIT	Del 557–558	11.0%
2014-BZ0028	17 of KIT	N822K	11.9%
2014-BZ0162	17 of KIT	N822K	19.8%
2014-BZ0096	17 of KIT	A814S	10.8%
2014-BZ0024	17 of KIT	N822K	22.8%
2014-BZ0135	17 of KIT	N822K	10.1%
2014-BZ0127	12 of PDGFRA	R585K	22.9%
2014-BZ0015	18 of PDGFRA	D842V	19.1%
2014-BZ0114	18 of PDGFRA	D842Y	10.3%
2014-BZ0038	18 of PDGFRA	D842V	18.1%

Note:

^*MutRatio = MutCount/Coverage ×100%.