Table 2. mRNAs expression levels of the indicated markers.
| CRC patients number (n) | CRC patientsMean ΔCt ± SD | Controls number | ControlsMean ΔCt ±SD | p-value | AUC | Sensitivity% | Specificity% | |
|---|---|---|---|---|---|---|---|---|
| TSPAN8 | 67 | 9.41 ± 2.00 | 67 | 11.33 ± 1.72 | 0.00000002 | 0.751 | 83.6 | 58.2 |
| EPCAM | 39 | 11.23 ± 1.36 | 36 | 11.83 ± 1.23 | 0.08 | 0.631 | - | - |
| SPINK 1 | 39 | 11.88 ± 2.87 | 36 | 11.85 ± 2.59 | 0.9 | 0.503 | - | - |
| COL1A2 | 67 | 9.59 ± 2.14 | 67 | 11.45 ± 1.92 | 0.0000005 | 0.718 | 73.1 | 59.7 |
| CDH1 | 39 | 9.9 ± 0.9 | 36 | 9.5 ± 1.08 | 0.2 | 0.581 | - | - |
| LGALS4 | 67 | 14.43 ± 1.28 | 67 | 12.89 ± 1.97 | 0.0000004 | 0.746 | 82.1 | 61.2 |
| CEACAM6 | 67 | 13.23 ± 1.24 | 67 | 12.34 ± 1.89 | 0.0017 | 0.632 | 65.7 | 61.2 |
| Panel: TSPAN8 + LGALS4 | 67 | - | 67 | - | 0.861 | 92.54 | 67.16 |
Statistical values between CRC patients and controls, AUC from ROC curves, sensitivities, specificities are reported
‘CRC’: colorectal cancer; ‘ΔCt'': delta cycle threshold; ‘Ct’: threshold cycle; ‘SD’: standard deviation; ‘AUC’: area under the ROC curve. p-value: 2-way Anova.