Figure 3. BMS-202 binds inside a cylindrical cleft at PD-L1 dimer interface.
Hydrophobic pocket accommodating the inhibitor and formed at PD-L1 dimer interface is shown from the solvent accessible side (stereoview). N-(2-aminoethyl)acetamide moiety of the inhibitor is visible. The PD-L1 molecules forming the dimer are colored blue and green for chain A and B, respectively.