Table 3. Clinical features and CK19 mRNA levels in SLN(+) patients.
nSLN Negative (N = 22) | nSLN Positive (N = 38) | P-value | ||
---|---|---|---|---|
Age(years) | 48.00 ± 5.92 | 49.58 ± 7.78 | 0.250 | |
Menopause | No | 14 | 24 | 0.970 |
Yes | 8 | 14 | ||
Tumor size(mm) | 32.27 ± 15.78 | 36.53 ± 19.10 | 0.307 | |
Total umber of positive lymph nodes | 1.45 ± 0.51 | 11.95 ± 8.42 | 0.000* | |
Grade | 1 | 2 | 2 | 0.487 |
2 | 14 | 20 | ||
3 | 6 | 16 | ||
lymphatic vessel invasion | No | 4 | 2 | 0.108 |
Yes | 18 | 36 | ||
HER2 | Positive | 8 | 12 | 0.705 |
Negative | 14 | 8 | ||
ER | Positive | 16 | 30 | 0.583 |
Negative | 6 | 8 | ||
PR | Positive | 16 | 28 | 0.936 |
Negative | 6 | 10 | ||
CK19 | Postive | 0 | 29 | 0.000*# |
Negative | 22 | 9 | ||
Copies of CK19 | 120.97 ± 198.16 | 1136.00 ± 602.03 | 0.000* |
Abbreviations: HER2, human epidermal growth factor receptor-2; ER, estrogen receptor; PR, progesterone receptor.
χ-test or t-test, p < 0.05.
Fisher's exact test, p < 0.05.