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. 2016 Apr 22;7(21):30702–30711. doi: 10.18632/oncotarget.8930

Figure 1. The expression of miR-638 was reduced in HCC cell lines and clinical specimens.

Figure 1

(A) qRT-PCR analysis of miR-638 expression in human normal hepatic cell line HL-7702 cells and HCC cell lines (MHCC-97L, HepG2, Hep3B, SMMC-7721 and MHCC-97H). (B) The average expression level of miR-638 in 100 HCC tissue samples compared with non-cancerous samples. (C) The average expression level of miR-638 in the high miR-638 expression group compared with the low miR-638 expression group. (D) The correlation between miR-638 expression and overall survival (OS) of the patients after surgery. Curves of OS were plotted by Kaplan-Meier methods according to miR-638 expression levels. HCC: hepatocellular carcinoma tissues. *P < 0.05, **P < 0.01, ***P < 0.001.