Table 2. Cox regression multivariate analysis of overall and disease-free survival in 60 patients with ESCC.

		Overall	Survival	Disease-Free	Survival
Variables	n	HR (95% CI)	P	HR (95% CI)	P
Age (years)
≤ 60	26	1		1
> 60	34	1.09 (0.40–2.94)	0.871	1.04 (0.41–2.67)	0.935
Gender
Female	8	1		1
Male	52	0.91 (0.30–2.81)	0.871	1.00 (0.32–3.10)	0.997
Drinking history (years)
≤ 10	11	1		1
> 10	49	0.93 (0.38–2.29)	0.877	0.87 (0.35–2.15)	0.768
Differentiation			0.392		0.307
Well	26	1		1
Moderate	16	1.28 (0.40–4.16)	0.680	1.07 (0.33–3.44)	0.915
Poor	18	0.62 (0.25–1.58)	0.320	0.53 (0.21–1.34)	0.179
Tumor size (cm)
≤ 4	38	1		1
> 4	22	0.53 (0.19–1.51)	0.235	0.56 (0.20–1.55)	0.262
T Classification			0.073		0.132
T1	12	1		1
T2	14	1.17 (0.23–5.92)	0.852	1.28 (0.28–5.78)	0.747
T3	22	1.13 (0.27–4.74)	0.871	1.01 (0.26–3.89)	0.989
T4	12	5.06 (0.89–28.67)	0.067	3.63 (0.68–19.48)	0.132
N Classification			0.042		0.091
N0	35	1		1
N1	12	2.65 (0.52–13.38)	0.240	2.15 (0.43–10.64)	0.350
N2	13	8.82 (1.50–51.88)	0.016	5.75 (1.08–30.59)	0.040
TNM Stage			0.012		0.006
I	18	1		1
II	15	7.55 (1.60–35.74)	0.011	6.30 (1.48–26.90)	0.013
III	27	16.80 (2.28–123.78)	0.006	22.43 (3.19–157.92)	0.002
miR-675-5p expression
Low	16	1		1
High	44	10.32 (2.97–35.89)	< 0.001	14.32 (3.88–52.82)	< 0.001