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. 2016 Apr 18;7(21):30990–31000. doi: 10.18632/oncotarget.8824

Figure 3. KLF4 elevated human osteosarcoma cells migration.

Figure 3

a–d. KLF4 were overexpressed or knockdown in MG63 cells using lentivirus vectors. The effects of KLF4 on cell migration were examined by wound-healing assay. Bar graph quantification of migration distance. U, units. Results are representative of three independent experiments. *P<0.05, **p<0.01 and ***p<0.001 vs Ctr. e–g. Effects of KLF4 on the migration were examined by Matrigel migration assay in MG63 (e) and SaOS2 cells (g). Migrated cells were plotted as the average number of cells per field of view. Results are representative of three independent experiments. *P<0.05, **p<0.01 and ***p<0.001 vs Ctr. i–f. KLF4 were overexpressed in MG63 cells and its effect on cell migration were examined by Matrigel migration assay. Results are representative of three independent experiments. *P<0.05, **p<0.01 and ***p<0.001 vs Ctr.