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. 2016 Apr 22;7(21):31350–31360. doi: 10.18632/oncotarget.8912

Figure 6. CYB5R1 mRNA expression and survival in colon cancer data from the TCGA.

Figure 6

A. ROC curve for determining best discrimination thresholds of CYB5R1 mRNA reads for survival prediction. Arrow indicates chosen value for binary classification. AUC=Area under curve. B. Kaplan-Meier statistics for binary (low and high) classified CYB5R1 expression indicate shorter tumor specific survival for CYB5R1 high. Significance p-values indicate log-rank test results. Ratios on curves indicate the number of events over the number of patients per group. C, D. Cases with high CYB5R1 expression are significantly (t-test) more frequent among cases with lymph node metastasis (N+, C) and distant metastasis (M1, D), when compared to cases with low CYB5R1 expression.