. 2016 Apr 22;7(21):31393–31400. doi: 10.18632/oncotarget.8918

Table 3. Co-occurrence of IDH-1 R132H mutation and other molecular markers.

Glioma		Ki-67		p value	p53 mut		p value	MGMT		p value
Glioma		<30	≥30	p value	L	H	p value	L	H	p value
IDH-1^{R132H mut}		185	87	0.000	120	152	0.000	207	65	0.000
IDH-1^{R132H wt}		149	249	0.000	303	95	0.000	234	164	0.000
IDH-1^{R132H mut}	A	20	0	0.000	4	16	0.017	16	4	0.924
	AA	12	5		3	14		13	4
	pGBM	6	13		11	8		14	5
IDH-1^{R132H wt}	A	13	0	0.000	9	4	0.003	8	5	0.718
	AA	8	7		7	8		7	8
	pGBM	81	200		232	49		156	125
IDH-1^{R132H mut}	O	36	0	0.000	32	4	0.090	30	6	0.616
	AO	16	9		18	7		21	4
	OA	69	0		27	42		58	11
IDH-1^{R132H mut}	AOA	15	15	0.000	9	21	0.603	21	9	0.067
IDH-1^{R132H mut}	GBMO	4	8	0.000	3	9	0.603	7	5	0.067
IDH-1^{R132H wt}	OA	13	0	0.001	7	6	0.103	9	4	1.000
	AOA	13	12		9	16		17	8
	GBMO	10	4		10	4		10	4