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. 2016 Jul 8;95(27):e4005. doi: 10.1097/MD.0000000000004005

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Copyright © 2016 the Author(s). Published by Wolters Kluwer Health, Inc. All rights reserved.

This is an open access article distributed under the Creative Commons Attribution-NoDerivatives License 4.0, which allows for redistribution, commercial and non-commercial, as long as it is passed along unchanged and in whole, with credit to the author. http://creativecommons.org/licenses/by-nd/4.0

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Relationship between EBV DNA level in breast milk and SCM. (A) Within EBV positive breast milk samples those with SCM and “possible SCM” have higher EBV load compared to non-SCM samples. (B) In mothers with unilateral SCM higher breast milk EBV DNA levels are detected in the site of SCM. Each pair represents samples collected at the same time from the 2 mammary glands of 1 mother. (C–E) IL-8 concentration according to breast milk EBV DNA shedding. In SCM (C) and “possible SCM” samples (D) IL-8 concentrations are significantly higher in EBV DNA negative breast milk samples compared to EBV DNA positive samples, whereas in non-SCM samples (E) IL-8 concentrations are not different. SCM = subclinical mastitis.