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. 2016 Oct 7;95(40):e5085. doi: 10.1097/MD.0000000000005085

Figure 6.

Figure 6

Human prostate cancer cell migration is reduced with ADAM28 inhibition and increased with ADAM28 overexpression. (A) Cell count for LNCaP cells showing that human prostate cancer cell migration is significantly reduced with ADAM28 inhibition by KB-R7785 (10 μM). (B) Normal epithelial prostate RWPE1 cells exhibit significantly heightened migration when transfected with an ADAM28 expression vector when compared to cells transfected with empty vector. All cell counts were averaged from 5 high power fields of view (HPF). Data are represented as mean ± SEM, ∗P < 0.05; n = 5/treatment for (A) and n = 15/treatment for (B). ADAM = a disintegrin and metalloproteinase, HPF = high powered field, SEM = standard error of mean.