Table 4. Hazard ratios and 95% confidence intervals from women age 65+ years and continuously enrolled in Medicare randomized to either active hormone therapy or placebo in either the WHI Estrogen plus Progestin or Estrogen-Alone trials.

		Hormone Therapy (N=4142)	Placebo (N=4223)
Clinical Event	Data source	N(%)	N(%)	Hazard Ratio	95% Confidence Interval
Acute myocardial infarction	WHI Adjudicated	150 (3.6)	120 (2.8)	1.31	(1.03-1.67)
	Medicare Algorithm	127 (3.1)	101 (2.4)	1.29	(1.00-1.68)
Non-procedure related myocardial infarction	WHI Adjudicated	130 (3.1)	105 (2.5)	1.28	(0.99-1.66)
	Medicare Algorithm	111 (2.7)	82 (1.9)	1.38	(1.03-1.83)
Coronary revascularization	WHI-Adjudicated	181 (4.4)	171 (4.1)	1.09	(0.88-1.35)
	Medicare Algorithm	195 (4.7)	179 (4.2)	1.10	(0.89-1.35)

Adapted from Hlatky et al.⁷