Table 3. Twenty-six non diagnostic cases separated into those that were false negatives for malignancy and those cases where no malignancy was found. There were 11 false negative cases and 16 true negative cases. Ultimate diagnoses are listed along with the method of diagnosis.
Diagnosis (number of cases) | Method of ultimate diagnosis |
---|---|
False negatives for malignancy, n=11/234 (4.7%) | |
NSCLC adenocarcinoma [2] | Repeat EBUS-TBNA under general anaesthetic [1] |
Endobronchial biopsies at time of EBUS procedure [1] | |
NSCLC-large undifferentiated [1] | CT guided FNA |
Squamous cell lung cancer [1] | Lobectomy |
Melanoma [1] | Repeat EBUS-TBNA under general anaesthetic |
Lymphoma [2] | CT guided FNA |
Radiologically suspicious for malignancy but died before diagnosis [1] | |
Renal cell carcinoma [1] | Mediastinoscopy |
Small cell lung cancer [1] | CT guided fine needle aspiration |
Kaposi sarcoma [1] | Axillary LN biopsy under ultrasound |
No subsequent malignancy found, n=16/26 (61.5%) | |
Benign lymphadenopathy [13] | Monitored for 12 months with resolution of lymphadenopathy on CT chest [11] |
Repeat EBUS under general anaesthetic [1] | |
Mediastinoscopy [1] | |
Granulomatous inflammation [1] | Mediastinoscopy [1] |
Anthrasilicosis [1] | Mediastinoscopy |
Pericardial cyst [1] | Confirmed at EBUS using Doppler mode and stable on follow up CT scans |
NSCLC, non-small cell lung carcinoma; EBUS-TBNA, endobronchial ultrasound transbronchial needle aspiration; FNA, fine needle aspiration.