Table 2. Top enriched human phenotypes of putative target genes near predicted heart enhancers.
| Top enriched phenotypes | Binomial FDR Q-value | Binomial fold enrichment |
|---|---|---|
| Cardiac arrest | 6.81 × 10−89 | 2.0 |
| Sudden cardiac death | 7.84 × 10−89 | 2.0 |
| Sudden death | 3.67 × 10−84 | 3.1 |
| Syncope | 1.22 × 10−64 | 2.2 |
| Atrial fibrillation | 8.88 × 10−62 | 2.0 |
| Abnormal EKG | 4.89 × 10−44 | 2.0 |
| Ventricular tachycardia | 6.28 × 10−44 | 2.6 |
| Aortic dissection | 9.09 × 10−43 | 2.2 |
| Bicuspid aortic valve | 1.60 × 10−39 | 2.2 |
| Pointed chin | 9.10 × 10−35 | 2.0 |
| Aortic aneurysm | 1.13 × 10−34 | 2.3 |
| Prolonged QT interval | 3.91 × 10−34 | 2.2 |
EKG, electrocardiogram; FDR, false discovery rate corrected. Additional highly enriched terms are included in Supplementary Table 3.