Table 3.
Effects of treatments of type 1 diabetes in C57Bl6/mice on change in body weight, blood glucose, and serum lipids.
| Determination | Control (18) | Diabetic group (16) | Diabetic + salsalate group (12) | Diabetic + menhaden oil group (11) | Diabetic + salsalate + menhaden oil group (14) | Diabetic + resolvin D1 group (13) |
|---|---|---|---|---|---|---|
| Start weight (g) | 25.5 ± 0.3 | 25.6 ± 0.3 | 25.6 ± 0.4 | 25.0 ± 0.5 | 25.0 ± 0.5 | 26.8 ± 0.4 |
| Final weight (g) | 30.6 ± 0.9 | 25.6 ± 0.3a | 25.4 ± 0.5a | 27.0 ± 0.5a | 26.7 ± 0.3a | 24.7 ± 0.3a |
| Blood glucose (mg/dL) | 183.1 ± 5 | 491 ± 19a | 463 ± 19a | 546 ± 21a | 491 ± 20a | 480 ± 24a |
| Serum triglycerides (mg/dL) | 9.4 ± 1.0 | 12.4 ± 0.9 | 10.6 ± 0.9 | 8.2 ± 0.6 | 9.8 ± 1.1 | 11.5 ± 0.9 |
| Serum free fatty acids (mmol/L) | 0.47 ± 0.08 | 0.41 ± 0.05 | 0.44 ± 0.06 | 0.26 ± 0.04 | 0.32 ± 0.06 | 0.38 ± 0.11 |
| Serum cholesterol (mg/dL) | 20.0 ± 1.2 | 26.8 ± 1.4 | 28.6 ± 4.0 | 34.2 ± 3.8a | 32.0 ± 3.6a | 27.3 ± 1.1 |
Data are presented as the mean ± SEM. a p < 0.05 compared to control mice. Numbers in parentheses indicate the number of experimental animals.