Table 2.
The correlation of oxidative stress parameters with heme oxigenase-1 expression and activity in hypertensive (n = 12) and normotensive rats (n = 12).
| L-HO-1 | HO-1 | BIL-D | BIL-T | |||||
|---|---|---|---|---|---|---|---|---|
| W | SHR | W | SHR | W | SHR | W | SHR | |
| L-TBARS | 0.0775 p = 0.811 |
0.6284 p = 0.029 |
−0.1981 p = 0.537 |
0.6444 p = 0.024 |
0.0034 p = 0.992 |
0.7475 p = 0.005 |
0.2548 p = 0.424 |
0.5980 p = 0.040 |
| p-TBARS | −0.2623 p = 0.410 |
−0.7715 p = 0.003 |
−0.0377 p = 0.908 |
−0.3397 p = 0.280 |
0.0890 p = 0.783 |
−0.7623 p = 0.004 |
0.0614 p = 0.850 |
−0.5674 p = 0.054 |
| k-TBARS | 0.6801 p = 0.015 |
0.4457 p = 0.147 |
0.1703 p = 0.597 |
0.4521 p = 0.140 |
−0.4280 p = 0.165 |
0.0775 p = 0.811 |
0.2146 p = 0.503 |
0.4398 p = 0.153 |
SHR: spontaneously hypertensive rats that received vehicle or thyme extract; W: Wistar rats that received vehicle or thyme extract; L-TBARS, p-TBARS, and k-TBARS: liver thiobarbituric acid reactive substance, plasma thiobarbituric acid reactive substance, and kidney thiobarbituric acid reactive substances; quantity of L-HO-1 and p-HO-1: liver and plasma heme oxigenase-1 enzyme; BIL-D: direct bilirubin; BIL-T: total bilirubin. Marked correlations are significant at p < 0.050.