Table 5. Association of Different Severity of Hyperopia with Esotropia.

Type of exposure	No of Studies	Sample size	Overall effect			Heterogeneity		Reference
			OR (95%CI)	z score	P Value	I2,%	Q (P)
2-3D vs esotropia	2	12918	10.16 (1.58–65.38)	2.44	0.01	92%	0.0005	12,18
3-4D vs esotropia	2	12285	17.83 (10.17–31.25)	10.06	<0.0001	0%	0.5	12,18
4-5D vs esotropia	2	12062	41.01 (22.44–74.92)	12.08	<0.0001	0%	0.99	12,18
≥5D vs esotropia	2	12035	162.68 (40.91–646.89)	7.23	<0.0001	81%	0.02	12,18