Table 2. Gene ontology analyses for biological processes, molecular function and cellular components for differentially expressed genes in low 1-C F1 embryos compared to control F1 embryos.
| Biological process | GoTerms* | Genes* | P-value range** | Benjamini range** |
|---|---|---|---|---|
| Inflammatory and immune response | 31 | 68 | 3.5E-12–4.3E-4 | 5.0E-9–9.5E-3 |
| Blood coagulation, haemostasis, wound healing | 6 | 27 | 1.6E-7–3.0E-4 | 2.6E-5–7.4E-3 |
| Processing of proteins, carboxylic- and amino acids | 16 | 58 | 1.9E-7–3.0E-4 | 2.5E-5–7.4E-3 |
| Lipid transport and metabolic processing | 19 | 37 | 4.1E-7–3.8E-4 | 3.7E-5–8.8E-3 |
| Oxidation reduction | 1 | 20 | 2.5E-4 | 1.6E-4 |
| Molecular function | GoTerms | Genes | P-value range | Benjamini range |
| Peptidase inhibitor activity | 4 | 13 | 1.3E-9–1.7E-5 | 3.3E-12–1.7E-7 |
| Oxidoreductase activity | 3 | 21 | 3.6E-5–6.6E-3 | 4.7E-4–2.4E-4 |
| Lipid transport | 2 | 8 | 4.1E-5–7.8E-3 | 6.4E-7–3.1E-4 |
| Other significant processes | 8 | 39 | 9.3E-4–9.3E-3 | 1.7E-5–3.8E-4 |
| Cellular component | GoTerms | Genes | P-value range | Benjamini range |
| Extracellular space and region | 3 | 47 | 8.9E-18–2.4E-10 | 1.9E-15–1.8E-8 |
| Vesicle lumen, platelet–and secretory granules | 4 | 8 | 8.7E-8–5.9E-6 | 4.6E-6–1.8E-4 |
In each ontology, the most enriched groups of significant GO terms, with the number of GO terms, genes and p-value range and Benjamini range are listed. *For a complete list of significantly differentially expressed genes enriched in each GO term please see Table S5.
**The p-value and Benjamini ranges refers to the highest and lowest GO term specific value for each group of GO terms.