Table 3. The effects of interval and continuous exercise regimens on mitochondrial biogenesis of lymphocytes.
| HIIT |
MICT |
CTL |
||||
|---|---|---|---|---|---|---|
| Pre | Post | Pre | Post | Pre | Post | |
| Phospho-AMPK (mean fluorescence intensity) | ||||||
| Rt | 73.5 ± 3.1 | 83.4 ± 3.5 | 85.2 ± 3.8 | 87.1 ± 4.3 | 81.3 ± 3.2 | 80.1 ± 4.0 |
| HE | 113.8 ± 2.8* | 95.5 ± 4.2 | 117.4 ± 4.9* | 97.0 ± 5.1 | 119.3 ± 4.0* | 117.0 ± 4.9* |
| SIRT (mean fluorescence intensity) | ||||||
| Rt | 22.6 ± 3.4 | 25.2 ± 3.0 | 23.4 ± 2.2 | 28.4 ± 3.0 | 23.9 ± 3.2 | 25.4 ± 3.2 |
| HE | 26.3 ± 3.7 | 25.8 ± 2.3 | 26.2 ± 4.6 | 25.6 ± 3.1 | 27.2 ± 3.5 | 29.6 ± 3.3 |
| PCG-1α (mean fluorescence intensity) | ||||||
| Rt | 29.2 ± 4.7 | 26.0 ± 3.9 | 27.4 ± 2.7 | 31.1 ± 4.5 | 29.3 ± 2.5 | 30.2 ± 4.2 |
| HE | 32.1 ± 4.9 | 28.3 ± 3.5 | 33.8 ± 3.8 | 26.0 ± 2.1 | 33.2 ± 3.5 | 33.0 ± 2.3 |
| NRF-1 (mean fluorescence intensity) | ||||||
| Rt | 65.0 ± 5.9 | 66.2 ± 6.1 | 65.1 ± 3.2 | 70.4 ± 6.7 | 69.1 ± 3.5 | 67.4 ± 6.0 |
| HE | 68.7 ± 5.4 | 78.3 ± 5.3 | 68.5 ± 4.6 | 73.7 ± 7.3 | 67.5 ± 4.2 | 70.5 ± 5.3 |
| Tfam (mean fluorescence intensity) | ||||||
| Rt | 41.5 ± 4.1 | 45.1 ± 4.8 | 41.4 ± 5.9 | 45.2 ± 4.2 | 43.4 ± 5.0 | 47.2 ± 4.5 |
| HE | 46.8 ± 3.2 | 52.1 ± 5.4 | 47.5 ± 4.0 | 53.2 ± 5.8 | 46.7 ± 4.8 | 53.0 ± 5.1 |
| Mitochondrial biogenesis (ratio of Complex IV to II) | ||||||
| Rt | 0.45 ± 0.07 | 0.46 ± 0.09 | 0.48 ± 0.05 | 0.50 ± 0.07 | 0.45 ± 0.05 | 0.49 ± 0.07 |
| HE | 0.50 ± 0.08 | 0.48 ± 0.08 | 0.45 ± 0.09 | 0.54 ± 0.07 | 0.55 ± 0.07 | 0.54 ± 0.08 |
Values were mean ± SE. HIIT, high-intensity interval training group; MICT, moderate-intensity continuous training group; CTL, control group; Pre, pre-intervention; Post, post-intervention; Rt, resting; HE, hypoxic exercise test. *P < 0.05, Rt vs. HE.