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. 2016 Sep 27;2016:9042019. doi: 10.1155/2016/9042019

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Copyright © 2016 Yibo Gan et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Measurement of the biochemical content of the hybrids including (a) DNA, (b) GAG, and (c) HYP of the MSCs-seeded dextran/gelatin hydrogels encapsulated with no supplement (control), 1000 μg/mL blank PLGANPs (PLGANPs), 1000 μg/mL TGF-β3-loaded PLGANPs (TGF-β3-PLGANPs), and the hydrogels with no supplements cultured in the medium containing 10 ng/mL TGF-β3 (TGF-β3) for 7, 14, and 28 days. Data were expressed as means ± SD (n = 3). The samples indicated with (∗) had a significant difference between the two groups (p < 0.05). The samples indicated with (A) had a significant difference compared to the same group on day 7 (p < 0.05) and (B) had a significant difference compared to the same group on day 14 (p < 0.05).