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. 2016 Sep 27;2016:1947819. doi: 10.1155/2016/1947819

Table 1.

Chromosome aberrations in bone marrow cells from LDLTR radiated mice.

Dose (Gy) Treatment TCC TAM TAC Fragments Gaps Dicentrics RT DLE EX ACR (%)
CMT CTT CMT CTT CMT CTT Mean SD
.0a Nonhydrogen 828 144 148 84 18 12 16 4 6 6 0 2 17.420 3.097
Hydrogen 842 146 148 84 12 4 14 14 10 10 0 0 17.380 1.731

.1ab Nonhydrogen 848 164 164 98 22 14 12 4 10 2 2 0 19.349 1.758
Hydrogen 852 152 154 108 16 8 8 8 4 2 0 0 17.865 2.852

.5ab Nonhydrogen 898 192 192 130 26 10 4 18 6 2 2 0 21.390 4.122
Hydrogen 840 144 146 78 20 8 16 10 8 6 0 0 17.117 1.135

1.0b Nonhydrogen 826 192 198 104 28 14 26 4 12 6 2 2 23.222 1.038
Hydrogen 830 152 154 70 32 4 12 6 12 18 0 0 18.286 2.016

2.0c Nonhydrogen 834 296 298 170 50 18 16 20 8 16 0 0 35.485 3.298
Hydrogen 858 244 244 134 22 8 30 10 26 8 4 2 28.350 3.207

All sorts of CAs are scored and displayed here. In each group, eight mice were included for this evaluation, with at least 100 metaphases examined for each of them (n = 8). Dose: radiation doses exposed to animals; treatment: whether treating the subjects with hydrogen or not; TCC: total counted cells. TAM: total aberrant metaphases. TAC: total aberrant chromosomes. CMT: chromosomal type; CTT: chromatid type. RT: Robertsonian translocation. DEL: deletion. EX: exchange.

Aberrant cells rate were compared with the method of two-way ANOVA. As for the radiation factor, F = 81.457 and p = 0.000; hydrogen: F = 37.349 and p = 0.000. Furthermore, there existed statistically interaction between radiation and hydrogen treatment (F = 4.662, p = 0.002). The LSD-test was selected for the subsequent comparisons between each radiation dose group.

The aberrant cells rates of groups that have totally different superscripts are significantly different from each other (p < 0.05 as significant, SNK test was used here).