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. 2016 Oct 12;6:35201. doi: 10.1038/srep35201

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Copyright © 2016, The Author(s)

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(a) The cell potential spatial regionalisation. (b) The protein regionalisation. (c) The time relaxations of V and p for the central cell marked by the arrow. We consider the positive regulation case of Fig. 1 with in Fig. 2c. The horizontal bars are the scales of V and p. Initially, the cell potentials are locally depolarised (V = −2.4 mV) at the two small regions while they are polarised (V = −59 mV) in the rest of the system. The rate and degradation constants are those of Fig. 2. At short times, the electrical relaxation gives a predominantly depolarised ensemble. At long times, the genetic relaxation results in low values of the protein concentration. The subscripts pol and dep make reference to the polarised and depolarised values, respectively.

Inline graphic — (a) The cell potential spatial regionalisation. (b) The protein regionalisation. (c) The time relaxations of V and p for the central cell marked by the arrow. We consider the positive regulation case of Fig. 1 with in Fig. 2c. The horizontal bars are the scales of V and p. Initially, the cell potentials are locally depolarised (V = −2.4 mV) at the two small regions while they are polarised (V = −59 mV) in the rest of the system. The rate and degradation constants are those of Fig. 2. At short times, the electrical relaxation gives a predominantly depolarised ensemble. At long times, the genetic relaxation results in low values of the protein concentration. The subscripts pol and dep make reference to the polarised and depolarised values, respectively.