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. 2016 Oct 12;6:35267. doi: 10.1038/srep35267

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Western blot analysis of apoptosis-related proteins expression (panel A) and drug resistance-related proteins expression (panel B) in MDA-MB-231/ADR cells after cells were treated with free DOX, free RES, MIX and DOX/RES-loaded NPS for 24 h. Data are mean ± SD. n = 3, *p < 0.05, **p < 0.01, vs PBS.